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Methotrexate is an antimetabolite medicine, as it impacts cell metabolic rate. It could be prescribed for managing active rheumatoid arthritis, breast cancer, skin psoriasis, and some various other conditions associated to fast and unusual development of cells in the body. This medication can be carried out by mouth, as well as infused intramuscularly or intravenously. Methotrexate is most frequently given regular, unless recommended or else by the medical professional.